The relationship of spinach to colon cancer .. a recent study answers

 The relationship of spinach to colon cancer .. a recent study answers

The leaves have always played an important role in protecting humans from diseases, especially tumors, as recent studies have shown that spinach prevents them from being linked to the colon.

US researchers believe that a diet rich in spinach can significantly reduce the formation of colon tumors, and even protect against colon cancer.

Spinach is a nutrient-rich leafy vegetable that contains many important micronutrients and includes a wide range of vitamins and minerals.

Spinach is also rich in dietary fiber, protein and fatty acids that are essential for tissue maintenance, improvement and regulation.

According to the Centers for Disease Control and Prevention (CDC), colon and rectal cancers are the fourth most common cancer, and the third leading cause of cancer death in the United States.

Eating spinach prevents colon cancer

Previous studies have shown that eating green vegetables and fiber reduces the risk of colon cancer by up to half.

But the new study, led by Texas A&M University Health Sciences Center researchers and recently published in the journal Gut Microbes, explores the relationship between spinach, gut bacteria, and genetics.

The study found that vegetables can prevent the growth of polyps in people with non-hereditary or genetic colon cancer, and also concluded that spinach's anti-polyposis effect stems from some surprising metabolic interaction.

Better than platinum.. spinach increases fuel cell efficiency

In the study, researchers used a model of an inherited disease called familial adenomatous polyposis, an inherited colorectal cancer disorder that causes young people to develop multiple noncancerous growths (polyps).

Most people with this disease must surgically remove the colon to prevent hundreds of tumors from growing in the colon as they age.

They then undergo treatment with toxic NSAIDs to prevent additional tumors from forming in the duodenum, the first part of the small intestine.

The results of the study indicate that spinach may help prevent cancer in these patients by delaying the need for colectomy and drug therapy for long periods.

After feeding dried spinach to an animal model of familial adenomatous polyposis for 26 weeks, the researchers observed significant antitumor activity in the colon and small intestine, which retards polyp growth and hampers the need for intensive treatment.

They found that tumor suppression by spinach involved increased diversity in the gut microbiome (the beneficial microbes) and changes in gene expression to help prevent cancer.

They also found that fatty acids linked to regulating inflammation, called "linoleate metabolites," were raised to a beneficial level after a spinach diet.

"We believe that eating spinach can also be protective for people without familial adenomatous polyposis," said lead researcher Roderick Dashwood, director of the Center for Epigenetics and Disease Prevention at Texas A&M Institute.

Dashwood previously noted the benefits of spinach in a cancer-inducible model of colorectal cancer that mimics sporadic cases.

In this model, spinach was so effective at preventing polyps, which led the team to find out how spinach might work in gene-induced colon cancer.

Multiple benefits of spinach

• Spinach offers plenty of health benefits anyway, explains cardiologist Michelle Rothenstein, the owner of Complete Nutrition who was not involved in this study.
• "Spinach contains many nutrients that help protect the health of your heart," Rothenstein told medicalnewstoday.
• She added: "Spinach is a rich source of vitamin K1, which has been shown to help reduce the risk of an enlarged heart, and is also rich in glutathione, which boosts the body's main antioxidant pathway, addresses oxidative stress and supports immune function."
• And she continued, "Spinach also contains folic acid, which is one of the vitamins needed to lower homocysteine ​​levels in the body, as its high leads to the promotion of plaque in the arteries."
• News-Medical has listed a number of other benefits of eating spinach, including:
• It has lipid-lowering properties and protects the heart and blood vessels.
• Rich in anti-inflammatory, anti-obesity, anti-diabetic (hypoglycemic activity) and anti-cancer properties, in addition to neurological effects.
• An excellent supplier of Vitamin A, Pro-Vitamin A, Vitamin K, Vitamin C, Vitamin B2, Vitamin C, Vitamin E and Vitamin K.
• Rich in minerals magnesium, calcium, potassium, zinc, copper, manganese, sodium, phosphorous and iron.
• A major source of dietary fiber, vitamin B6 and omega-3 fatty acids.

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